techletter by Nesibe

techletter by Nesibe

When an LLM Starts Thinking With Living Neurons

How a biocomputer with 200,000 living human neurons is quietly reshaping the future of AI, energy, and consciousness debates.

Nesibe | AI Governance Expert's avatar
Nesibe | AI Governance Expert
Mar 04, 2026
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Hey everyone, I’m genuinely challenging myself to keep you updated. This is a lot of work: tracking news not daily but hourly, digging into background, sketching possible scenarios, assessing governance risks so you can see around corners, and then writing it all up here. Of course, I do lean on AI tools in the background to help me organise and clean up the flow, but every line you read is still my judgement and my voice: less machine, more us.

Over the next few weeks you’ll probably see some version of this headline in your feed:

“They hooked a live brain up to an LLM. 200,000 human neurons decide where the AI wants to go on vacation.”

The story is kind a real. A solo developer rented Cortical Labs’ CL1 “biocomputer”, wired it into a small language model, and let 200,000 lab‑grown human neurons nudge the model’s token choices in real time.​​

It feels like a Matrix moment. But it is not. I have always thought that what American scifiction showed us is actually what they are on it and try…

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